SELECTED PUBLICATIONS

2026
Holt R, Evgin L. A gene-editing method generates immunotherapeutic CAR T cells in the body. Nature. 2026 652(8110):572-574. PMID: 41851543.
Savage G, Milne K, Collinge B, Yin Y, Loos P, Warren ME, Laumont CM, Keith D, Nelson BH, Venturutti L, Weng AP, Scott DW, Steidl C, Evgin L. Phenotypic Characterization and Prognostic Impact of CD103+ Tissue-Resident Memory T Cells in Diffuse Large B-cell Lymphoma. Cancer Immunol Res. 2026;14(2):291-306. PMID: 41270222
2025
Bernard G, Evgin L. Non-signaling but all important: how the linker, hinge, and transmembrane domains in the CAR hold it all together. Front Immunol. 2025;16:1664403.PMID: 41221288
2024
Short L, Holt RA, Cullis PR, Evgin L. Direct in vivo CAR T cell engineering. Trends Pharmacol Sci. 2024;45(5):406-418. PMID: 38614815.
2023
Loos P, Short L, Savage G, Evgin L. Expansion and Retroviral Transduction of Primary Murine T Cells for CAR T-Cell Therapy. Methods Mol Biol. 2024;2748:41-53.
Alvarez-Breckenridge C, Anderson KG, Correia AL, Demehri S, Dinh HQ, Dixon KO, Dunn GP, Evgin L, Goc J, Good Z, Hacohen N, Han P, Hanč P, Hickey J, Kersten K, Liu BC, Buque A, Miao Y, Milner JJ, Pritykin Y, Pucci F, Scharping NE, Sudmeier L, Wang Y, Wieland A, Williams MM. Lessons for the next generation of scientists from the 2nd annual Arthur and Sandra Irving Cancer Immunology Symposium. Cancer Immunology Research. Cancer Immunol Res. 2023 Oct 31:OF1-OF7.
2022
Evgin L, Kottke T, Tonne J, Thompson J, Huff AL, van Vloten J, Moore M, Michael J, Driscoll C, Pulido J, Swanson E, Kennedy R, Coffey M, Loghmani H, Sanchez-Perez L, Olivier G, Harrington K, Pandha H, Melcher A, Diaz RM, Vile RG. Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice. Sci Transl Med. 2022 Apr 13;14(640):eabn2231.
2021
Evgin L, Vile RG. Parking CAR T Cells in Tumours: Oncolytic Viruses as Valets or Vandals? Cancers (Basel). 2021 Mar 5;13(5):1106.
2020
Evgin L, Huff AL, Wongthida P, Thompson J, Kottke T, Tonne J, Schuelke M, Ayasoufi K, Driscoll CB, Shim KG, Reynolds P, Monie DD, Johnson AJ, Coffey M, Young SL, Archer G, Sampson J, Pulido J, Perez LS, Vile R. Oncolytic virus-derived type I interferon restricts CAR T cell therapy. Nat Commun. 2020 Jun 24;11(1):3187